Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 2/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12818788 | 0.80 | CD38 (0.41) | MAPTKDM4ECD38ALDH1A1HPGD | |
| SCHEMBL22181623 | 0.77 | MYC (0.39) | MAPTTP53KDM4ENPC1L3MBTL1 | |
| SCHEMBL12525192 | 0.77 | GRM5 (0.42) | MAPTKDM4EPDE1APDE1BPDE1C | |
| SCHEMBL26921312 | 0.76 | CD38 (0.35) | CD38KLKB1SSTR4TRPC5 | |
| SCHEMBL29995766 | 0.76 | CD38 (0.35) | CD38KLKB1SSTR4TRPC5 | |
| SCHEMBL21503569 | 0.75 | KCNA5 (0.36) | PDE1APDE1BPDE1CGRM5CD38 | |
| SCHEMBL28051170 | 0.74 | CD38 (0.36) | MAPTKDM4ECD38SSTR4HTT | |
| SCHEMBL27863522 | 0.74 | NOS3 (0.44) | MAPTKDM4ENPC1L3MBTL1BRD4 | |
| SCHEMBL1810170 | 0.74 | CYP11B1 (0.42) | MAPTTP53KDM4ENPC1L3MBTL1 | |
| SCHEMBL13066846 | 0.73 | CD38 (0.36) | MAPTKDM4EL3MBTL1PDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |