Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128382 | 0.82 | CD38 (0.36) | CD38HDAC6TRPC5RBP4HTT | |
| SCHEMBL12818788 | 0.82 | CD38 (0.41) | CD38HDAC6TRPC5RBP4HTT | |
| SCHEMBL30612302 | 0.82 | KDM4E (0.42) | CD38HDAC6TRPC5RBP4HTT | |
| SCHEMBL13066846 | 0.82 | CD38 (0.36) | CD38HDAC6TRPC5RBP4HTT | |
| SCHEMBL844943 | 0.82 | KDM4E (0.42) | CD38HDAC6TRPC5RBP4HTT | |
| SCHEMBL29392684 | 0.82 | DPP4 (0.42) | CD38HDAC6TRPC5RBP4HTT | |
| SCHEMBL738750 | 0.82 | TRPC5 (0.37) | CD38HDAC6TRPC5RBP4HTT | |
| SCHEMBL843961 | 0.82 | CD38 (0.36) | CD38HDAC6TRPC5RBP4HTT | |
| SCHEMBL2348709 | 0.82 | DPP4 (0.42) | CD38HDAC6TRPC5RBP4HTT | |
| Hydrochloric Acid SCHEMBL17292826 | 0.80 | DPP4 (0.41) | CD38HDAC6TRPC5RBP4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218565-A | Spiral shell oxindole compounds and the purposes as therapeutical agent thereof | XENON PHARMACEUTICALS INC | 2016-01-06 | — | — | CN | disclosed |