Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NRP1 | O14786 | 7/20 | 0.75 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | NPY4R | P50391 | 4/20 | 0.37 |
| ▸ | NPY1R | P25929 | 3/20 | 0.37 |
| ▸ | NPY2R | P49146 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.36 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24484800 | 0.98 | NRP1 (0.73) | NRP1F2NPY4RNPY1RNPY2R | |
| SCHEMBL24485890 | 0.80 | NRP1 (0.56) | NRP1F2NPY4RNPY1RNPY2R | |
| SCHEMBL24485496 | 0.79 | NRP1 (0.51) | NRP1F2FNTAFNTBPGGT1B | |
| SCHEMBL24484848 | 0.79 | NMUR2 (0.49) | NRP1F2NMUR2NMUR1 | |
| SCHEMBL16527042 | 0.78 | NRP1 (0.61) | NRP1F2 | |
| SCHEMBL19264001 | 0.78 | NRP1 (0.61) | NRP1F2 | |
| SCHEMBL24485493 | 0.77 | F2 (0.49) | NRP1F2NMUR2NMUR1 | |
| SCHEMBL24484834 | 0.77 | NMUR2 (0.48) | NRP1F2NMUR2NMUR1 | |
| SCHEMBL19263866 | 0.76 | NRP1 (0.55) | NRP1F2 | |
| SCHEMBL16527031 | 0.76 | NRP1 (0.55) | NRP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169677-A1 | NRP-1 BINDING INHIBITORY PEPTIDES AND USES THEREOF | UNIVERSITÉ PARIS CITÉ (FR) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169677-A1 | NRP-1 BINDING INHIBITORY PEPTIDES AND USES THEREOF | NRP1, KDR, FLT1 | NRP1 1/4885F2 4769/4885NPY4R 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.