Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.49 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.49 |
| ▸ | NRP1 | O14786 | 5/20 | 0.49 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24484834 | 0.98 | NMUR2 (0.48) | NMUR2NMUR1NRP1BDKRB2F2 | |
| SCHEMBL30811116 | 0.88 | NMUR2 (0.53) | NMUR2NMUR1NRP1BDKRB2F2 | |
| SCHEMBL32690530 | 0.87 | NMUR2 (0.49) | NMUR2NMUR1NRP1BDKRB2F2 | |
| SCHEMBL24485555 | 0.82 | BDKRB2 (0.47) | NMUR2NMUR1NRP1BDKRB2 | |
| SCHEMBL24485557 | 0.81 | NMUR2 (0.41) | NMUR2NMUR1BDKRB2F2PRSS1 | |
| SCHEMBL19264001 | 0.80 | NRP1 (0.61) | NRP1F2 | |
| SCHEMBL16527042 | 0.80 | NRP1 (0.61) | NRP1F2 | |
| SCHEMBL24485491 | 0.79 | NRP1 (0.75) | NMUR2NMUR1NRP1F2 | |
| SCHEMBL19263866 | 0.79 | NRP1 (0.55) | NRP1F2 | |
| SCHEMBL16527031 | 0.79 | NRP1 (0.55) | NRP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169677-A1 | NRP-1 BINDING INHIBITORY PEPTIDES AND USES THEREOF | UNIVERSITÉ PARIS CITÉ (FR) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169677-A1 | NRP-1 BINDING INHIBITORY PEPTIDES AND USES THEREOF | NRP1, KDR, FLT1 | NMUR2 482/4885NMUR1 197/4885NRP1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.