Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | SLC26A4 | O43511 | 7/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29629923 | 1.00 | CASP3 (0.47) | CASP3SENP8SENP7SENP6SLC26A4 | |
| SCHEMBL24485717 | 0.96 | CASP3 (0.48) | CASP3SENP8SENP7SENP6SLC26A4 | |
| SCHEMBL29630183 | 0.96 | CASP3 (0.48) | CASP3SENP8SENP7SENP6SLC26A4 | |
| SCHEMBL29629696 | 0.93 | CASP3 (0.46) | CASP3SENP8SENP7SENP6SLC26A4 | |
| SCHEMBL24484791 | 0.93 | CASP3 (0.46) | CASP3SENP8SENP7SENP6SLC26A4 | |
| SCHEMBL24485637 | 0.92 | CASP3 (0.48) | CASP3SENP8SENP7SENP6SLC26A4 | |
| SCHEMBL29629917 | 0.92 | CASP3 (0.48) | CASP3SENP8SENP7SENP6SLC26A4 | |
| SCHEMBL24485632 | 0.91 | CASP3 (0.45) | CASP3SENP8SENP7SENP6SLC26A4 | |
| SCHEMBL29629894 | 0.91 | CASP3 (0.45) | CASP3SENP8SENP7SENP6SLC26A4 | |
| SCHEMBL30719729 | 0.87 | L3MBTL1 (0.38) | PTGS2L3MBTL1TSHRKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |