Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515452 | 1.00 | PTGS2 (0.51) | PTGS2TP53TDP1BCL2TAAR1 | |
| SCHEMBL29434177 | 1.00 | PTGS2 (0.51) | PTGS2TP53TDP1BCL2TAAR1 | |
| SCHEMBL29434194 | 0.87 | BCL2 (0.47) | PTGS2TP53TDP1BCL2TGFBR1 | |
| SCHEMBL4517268 | 0.87 | BCL2 (0.47) | PTGS2TP53TDP1BCL2TGFBR1 | |
| SCHEMBL29434161 | 0.86 | PTGS2 (0.49) | PTGS2TP53TDP1TAAR1KCNH2 | |
| SCHEMBL5034588 | 0.86 | PTGS2 (0.49) | PTGS2TP53TDP1TAAR1KCNH2 | |
| SCHEMBL595061 | 0.84 | PTGS2 (0.59) | PTGS2TP53TDP1TRIM24TRIM33 | |
| SCHEMBL4508221 | 0.82 | BCL2 (0.54) | PTGS2TP53TDP1BCL2ALDH1A1 | |
| SCHEMBL5735233 | 0.82 | TRIM24 (0.56) | PTGS2TDP1BCL2TRIM24TRIM33 | |
| SCHEMBL8436350 | 0.81 | HSD11B1 (0.48) | PTGS2TP53ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008330-A1 | COMBINED INHIBITION OF AMINO ACID TRANSPORTERS FOR INHIBITING HUMAN PLASMACYTOID DENDRITIC CELL ACTIVITY DURING AUTOIMMUNITY | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2022-06-08 | — | — | EP | disclosed |