Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29577973 | 1.00 | SMN1; SMN2 (0.62) | SMN1; SMN2PDCD1CD274GLAMAPT | |
| SCHEMBL12758444 | 0.89 | PDCD1 (0.58) | SMN1; SMN2PDCD1CD274GLAMAPT | |
| SCHEMBL13545935 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTTP53ALDH1A1MEN1 | |
| SCHEMBL29694087 | 0.82 | ALDH1A1 (0.62) | SMN1; SMN2PDCD1CD274MAPTTP53 | |
| SCHEMBL24489089 | 0.82 | ALDH1A1 (0.62) | SMN1; SMN2PDCD1CD274MAPTTP53 | |
| SCHEMBL15508241 | 0.79 | SMN1; SMN2 (0.65) | SMN1; SMN2MAPTTP53ALPLNPC1 | |
| SCHEMBL12721619 | 0.76 | HPGD (0.59) | SMN1; SMN2PDCD1CD274GLATP53 | |
| SCHEMBL21446821 | 0.75 | F10 (0.54) | SMN1; SMN2PDCD1CD274GLAMAPT | |
| SCHEMBL12758441 | 0.74 | KMT2A (0.60) | SMN1; SMN2TP53NPC1RAB9AALDH1A1 | |
| SCHEMBL10160826 | 0.74 | NPC1 (0.66) | SMN1; SMN2MAPTTP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008717-A2 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |
| EP-4008716-A1 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |