Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24489005 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL24489088 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL6995919 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL5096639 | 0.80 | ALDH1A1 (0.73) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL24489002 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL7671472 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL7002682 | 0.78 | MAPT (0.59) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL7003377 | 0.77 | ALDH1A1 (0.80) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL24489106 | 0.77 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTNPSR1HPGD | |
| SCHEMBL24489136 | 0.76 | MAPT (0.62) | ALDH1A1KDM4EMAPTNPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008717-A2 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |