Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.67 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24489094 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTHPGDNPSR1 | |
| SCHEMBL24489106 | 0.83 | ALDH1A1 (0.76) | ALDH1A1KDM4EMAPTHPGDNPSR1 | |
| SCHEMBL7003377 | 0.83 | ALDH1A1 (0.80) | ALDH1A1KDM4EMAPTHPGDNPSR1 | |
| SCHEMBL24489113 | 0.83 | RAB9A (0.68) | ALDH1A1KDM4EMAPTHPGDNPSR1 | |
| SCHEMBL5096639 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KDM4EMAPTHPGDNPSR1 | |
| SCHEMBL24488965 | 0.80 | MRGPRX4 (0.55) | ALDH1A1KDM4EMAPTHPGDNPSR1 | |
| SCHEMBL24489088 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAPTHPGDNPSR1 | |
| SCHEMBL7002981 | 0.79 | MAPT (0.65) | ALDH1A1KDM4EMAPTHPGDNPSR1 | |
| SCHEMBL7002312 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTHPGDNPSR1 | |
| SCHEMBL24489117 | 0.77 | ALDH1A1 (0.70) | ALDH1A1KDM4EMAPTHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4008717-A2 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |
| EP-4008716-A1 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |
| EP-4008716-A1 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |
| EP-4008717-A2 | NOVEL INHIBITORS OF INSULIN-LIKE GROWTH FACTOR 2 MRNA BINDING PROTEINS | Martin-Luther-Universität Halle-Wittenberg (DE) | 2022-06-08 | — | — | EP | disclosed |