Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 14/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 9/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.41 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GGT1 | P19440 | 3/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27112814 | 0.83 | GRIK1 (0.44) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL20333677 | 0.82 | GRIK1 (0.47) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL22060227 | 0.80 | GRIK1 (0.62) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL24501833 | 0.80 | GRIK1 (0.62) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL13452270 | 0.76 | GRIK1 (0.41) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL24489498 | 0.75 | KDM4E (0.35) | — | |
| SCHEMBL27112972 | 0.73 | GRIK1 (0.33) | GRIK1GRIK2GRM1GRM2 | |
| SCHEMBL12698624 | 0.71 | GRIK1 (0.47) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL20630478 | 0.71 | GRIK1 (0.47) | GRIK1GRIK2GRM1GRM2SLC7A5 | |
| SCHEMBL21700142 | 0.70 | GRIK1 (0.41) | GRIK1GRIK2GRM1GRM2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067599-A1 | IODOTYROSINE DERIVATIVES AND PROCESS FOR PREPARING IODOTYROSINE DERIVATIVES | ABX ADVANCED BIOCHEMICAL COMPOUNDS - BIOMEDIZINISCHE FORSCHUNGSREAGENZIEN GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| WO-2022117590-A1 | IODOTYROSINE DERIVATIVES AND PROCESS FOR PREPARING IODOTYROSINE DERIVATIVES | ABX ADVANCED BIOCHEMICAL COMPOUNDS - BIOMEDIZINISCHE FORSCHUNGSREAGENZIEN GMBH (DE) | 2022-06-09 | — | — | WO | disclosed |
| EP-4008713-A1 | IODINE TYROSINE DERIVATIVES AND METHOD FOR THE PREPARATION OF IODINE TYROSINE DERIVATIVES | ABX Advanced Biochemical Compounds GmbH (DE) | 2022-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240067599-A1 | IODOTYROSINE DERIVATIVES AND PROCESS FOR PREPARING IODOTYROSINE DERIVATIVES | ALK, ALKBH3, INSR | GRIK1 2088/4885GRIK2 3018/4885GRM1 1468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.