Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 8/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22461454 | 0.92 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3BTK | |
| SCHEMBL22461450 | 0.92 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3BTK | |
| SCHEMBL22460910 | 0.84 | SLC6A2 (0.41) | NPC1SLC6A2SLC6A4SLC6A3BTK | |
| SCHEMBL24489979 | 0.83 | BTK (0.39) | SLC6A2SLC6A4SLC6A3BTK | |
| SCHEMBL22461455 | 0.83 | BTK (0.44) | SLC6A2SLC6A4SLC6A3BTK | |
| SCHEMBL22461190 | 0.83 | BTK (0.44) | SLC6A2SLC6A4SLC6A3BTK | |
| SCHEMBL24489998 | 0.82 | SLC6A2 (0.62) | MAPTALDH1A1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL22461555 | 0.82 | SLC6A2 (0.62) | MAPTALDH1A1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL24490161 | 0.81 | ESR1 (0.44) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL24490216 | 0.77 | KIF11 (0.47) | MAPTALDH1A1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177488-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | CIT THERAPEUTICS LLC | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177488-A1 | SUMO INHIBITOR COMPOUNDS AND USES THEREOF | SUMO1, SUMO2, SUMO3 | MAPT 2442/4885ALDH1A1 1950/4885NPC1 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.