Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228717 | 1.00 | ADRA1A (0.52) | ADRA1AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL13056634 | 1.00 | ADRA1A (0.52) | ADRA1AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL18532464 | 1.00 | ADRA1A (0.52) | ADRA1AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL22690587 | 1.00 | ADRA1A (0.52) | ADRA1AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL12197743 | 1.00 | ADRA1A (0.52) | ADRA1AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL19057218 | 1.00 | ADRA1A (0.52) | ADRA1AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL13248321 | 0.98 | ADRA1A (0.53) | ADRA1AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL22388820 | 0.93 | ADRA1A (0.46) | ADRA1AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL21788052 | 0.89 | ADRA1A (0.58) | ADRA1AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL26153487 | 0.88 | ADRA1A (0.44) | ADRA1AMEN1KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177489-A1 | Next Generation Synthetic Transcription Factors | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177489-A1 | Next Generation Synthetic Transcription Factors | ZFX, RUNX1, JUN | ADRA1A 4856/4885MEN1 2726/4885KMT2A 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.