Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.31 |
| ▸ | MC4R | P32245 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24491180 | 0.89 | FOLH1 (0.39) | FOLH1SIRT2SIRT1C3AR1ROCK2 | |
| SCHEMBL23974299 | 0.88 | FOLH1 (0.38) | FOLH1SIRT2SIRT1C3AR1DGAT1 | |
| SCHEMBL24451211 | 0.88 | DGAT1 (0.33) | FOLH1SIRT2SIRT1DGAT1SIRT3 | |
| SCHEMBL24451140 | 0.88 | DGAT1 (0.33) | FOLH1SIRT2SIRT1DGAT1SIRT3 | |
| SCHEMBL24472555 | 0.87 | FAP (0.32) | FOLH1SIRT2SIRT1DGAT1SIRT3 | |
| SCHEMBL24472556 | 0.87 | FAP (0.32) | FOLH1SIRT2SIRT1DGAT1SIRT3 | |
| SCHEMBL24491154 | 0.85 | FOLH1 (0.38) | FOLH1 | |
| SCHEMBL24479319 | 0.84 | DGAT1 (0.33) | FOLH1SIRT2SIRT1DGAT1SIRT3 | |
| SCHEMBL24450764 | 0.83 | FAP (0.33) | FOLH1SIRT2SIRT1DGAT1SIRT3 | |
| SCHEMBL24491200 | 0.80 | FOLH1 (0.36) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220175761-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | COHERENT BIOPHARMA SUZHOU LTD (CN) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175761-A1 | BI-LIGAND DRUG CONJUGATE AND USE THEREOF | SLC10A1, CD47, SELPLG | FOLH1 234/4885SIRT2 2300/4885SIRT1 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.