SCHEMBL2449239

SCHEMBL2449239

C=COc1ccc(/C=C/c2ccc(C(=O)O)cc2)cc1OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 3/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
CXCL12 P48061 1/20 0.53
CYP1A1 P04798 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP1B1 Q16678 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
MAPK1 P28482 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA12 O43570 1/20 0.51
CA4 P22748 1/20 0.51
CA6 P23280 1/20 0.51
CA7 P43166 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2449241 1.00 ABCG2 (0.54) ABCG2MEN1KMT2ACXCL12CYP1A1
SCHEMBL4254456 0.88 ABCG2 (0.67) ABCG2MEN1KMT2ACXCL12CYP1A1
SCHEMBL4254451 0.88 ABCG2 (0.67) ABCG2MEN1KMT2ACXCL12CYP1A1
SCHEMBL2453086 0.82 FDPS (0.56) ABCG2MEN1KMT2ACXCL12SMN1; SMN2
SCHEMBL2453084 0.82 CXCL12 (0.47) ABCG2MEN1KMT2ACXCL12CYP1A1
SCHEMBL5692941 0.82 TSHR (0.70) ABCG2MEN1KMT2ACXCL12CYP1A1
SCHEMBL5692937 0.82 TSHR (0.70) ABCG2MEN1KMT2ACXCL12CYP1A1
SCHEMBL5692902 0.80 CXCL12 (0.79) ABCG2MEN1KMT2ACXCL12CYP1A2
SCHEMBL5692905 0.80 CXCL12 (0.79) ABCG2MEN1KMT2ACXCL12CYP1A2
SCHEMBL5693342 0.78 PKM (0.61) MEN1KMT2ACXCL12CYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1422255-B1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY NIPPON OIL CORP (JP) 2011-09-28 EP disclosed
US-20100208182-A1 METHOD FOR MANUFACTURING OPTICAL FILM NIPPON OIL CORPORATION (JP) 2010-08-19 US disclosed
EP-2202546-A1 METHOD FOR PRODUCING OPTICAL FILM Nippon Oil Corporation (JP) 2010-06-30 EP disclosed
US-6894141-B2 Main chain type liquid crystalline polyester, liquid crystalline composition, method for producing liquid crystal film and optical film, and display having optical film NIPPON OIL CORPORATION (JP) 2005-05-17 US disclosed
US-20040171788-A1 Main chain type liquid crystal polyester, liquid crystalline composition, method for producing liquid crystal film, optical film and display NOBLE VENTURE FINANCE I LIMITED (GB) 2004-09-02 US disclosed
EP-1422255-A1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY Nippon Oil Corporation (JP) 2004-05-26 EP disclosed