Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22428510 | 0.95 | CYP19A1 (0.45) | CYP19A1CYP2A6MAPTCYP11B1GRM5 | |
| SCHEMBL21973988 | 0.91 | CYP19A1 (0.60) | CYP19A1CYP2A6MAPTCYP11B1CYP11B2 | |
| SCHEMBL24493058 | 0.89 | MEN1 (0.46) | CYP19A1CYP2A6MAPTCYP11B1GRM5 | |
| SCHEMBL23843484 | 0.89 | CYP19A1 (0.51) | CYP19A1CYP2A6MAPTCYP11B1GRM5 | |
| SCHEMBL24492872 | 0.88 | ATM (0.37) | CYP19A1CYP2A6MAPTCYP11B1GRM5 | |
| SCHEMBL24492882 | 0.87 | MAOA (0.38) | CYP19A1CYP2A6MAPTCYP11B1GRM5 | |
| SCHEMBL18560751 | 0.87 | MAPT (0.45) | CYP19A1CYP2A6MAPTCYP11B1GRM5 | |
| SCHEMBL22428569 | 0.87 | KMT2A (0.40) | MAPTGRM5DHODHKDM4ELMNA | |
| SCHEMBL22428571 | 0.87 | MKNK1 (0.44) | CYP19A1CYP2A6MAPTCYP11B1GRM5 | |
| SCHEMBL22428511 | 0.86 | MAOA (0.39) | CYP19A1MAPTGRM5KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177454-A1 | TRISUBSTITUTED BENZENE COMPOUND HAVING NITROGEN-CONTAINING HETERO RING IN MOLECULAR TERMINUS AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177454-A1 | TRISUBSTITUTED BENZENE COMPOUND HAVING NITROGEN-CONTAINING HETERO RING IN MOLECULAR TERMINUS AND ORGANIC ELECTROLUMINESCENCE ELEMENT | ETV6, LEF1, TEAD2 | CYP19A1 2451/4885CYP2A6 2586/4885MAPT 2481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.