Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24492822 | 0.96 | MKNK1 (0.42) | MKNK1PIK3CAMAPK10DYRK1ANOTUM | |
| SCHEMBL24493047 | 0.93 | CYP19A1 (0.40) | MKNK1PIK3CADYRK1AMAPTMEN1 | |
| SCHEMBL11987859 | 0.92 | MAPK10 (0.41) | MKNK1PIK3CAMAPK10MAPTMEN1 | |
| SCHEMBL24492827 | 0.91 | KDM4E (0.45) | MKNK1PIK3CADYRK1ANOTUMMAPT | |
| SCHEMBL24492900 | 0.90 | CYP19A1 (0.42) | MKNK1PIK3CADYRK1AMAPTMEN1 | |
| SCHEMBL25946455 | 0.90 | ATM (0.42) | MKNK1PIK3CAMAPK10DYRK1ANOTUM | |
| SCHEMBL24492823 | 0.89 | ATM (0.39) | MAPK10DYRK1AMAPTMEN1KMT2A | |
| SCHEMBL11987863 | 0.89 | KDM4E (0.41) | MKNK1MAPK10MAPTMEN1HSP90AA1 | |
| SCHEMBL13471366 | 0.89 | KIF11 (0.39) | MKNK1PIK3CAMAPK10DYRK1ANOTUM | |
| SCHEMBL12162410 | 0.87 | MAPK10 (0.40) | MKNK1PIK3CAMAPK10DYRK1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177454-A1 | TRISUBSTITUTED BENZENE COMPOUND HAVING NITROGEN-CONTAINING HETERO RING IN MOLECULAR TERMINUS AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177454-A1 | TRISUBSTITUTED BENZENE COMPOUND HAVING NITROGEN-CONTAINING HETERO RING IN MOLECULAR TERMINUS AND ORGANIC ELECTROLUMINESCENCE ELEMENT | ETV6, LEF1, TEAD2 | MKNK1 4036/4885PIK3CA 2890/4885MAPK10 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.