Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24492835 | 0.92 | CYP19A1 (0.46) | CYP19A1MAPTMEN1KMT2AHDAC8 | |
| SCHEMBL24492836 | 0.91 | MEN1 (0.36) | CYP19A1TNFMAPTMAPK10MEN1 | |
| SCHEMBL24492823 | 0.91 | ATM (0.39) | TNFMAPTMAPK10MEN1KMT2A | |
| SCHEMBL24492782 | 0.90 | ATM (0.42) | CYP19A1PIM1MAPTMEN1KMT2A | |
| SCHEMBL15369824 | 0.87 | CYP19A1 (0.54) | CYP19A1MAPTMEN1KMT2AHDAC8 | |
| SCHEMBL15369843 | 0.87 | CYP19A1 (0.41) | CYP19A1TNFMAPTMAPK10MEN1 | |
| SCHEMBL24492882 | 0.87 | MAOA (0.38) | CYP19A1PIM1TNFMAPTGRM5 | |
| SCHEMBL12169093 | 0.86 | KMT2A (0.33) | CYP19A1TNFMAPTMAPK10MEN1 | |
| SCHEMBL15369929 | 0.86 | CYP19A1 (0.43) | CYP19A1TNFMAPTMAPK10MEN1 | |
| SCHEMBL15369926 | 0.86 | CYP19A1 (0.43) | CYP19A1TNFMAPTMAPK10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177454-A1 | TRISUBSTITUTED BENZENE COMPOUND HAVING NITROGEN-CONTAINING HETERO RING IN MOLECULAR TERMINUS AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177454-A1 | TRISUBSTITUTED BENZENE COMPOUND HAVING NITROGEN-CONTAINING HETERO RING IN MOLECULAR TERMINUS AND ORGANIC ELECTROLUMINESCENCE ELEMENT | ETV6, LEF1, TEAD2 | CYP19A1 2451/4885PIM1 2564/4885TNF 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.