Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13185267 | 0.87 | HRH3 (0.43) | HRH3EP300ATMACHESLC6A4 | |
| SCHEMBL20771831 | 0.87 | EP300 (0.49) | EP300ACHEACACB | |
| SCHEMBL24493312 | 0.85 | HRH3 (0.46) | HRH3EP300SLC6A4ACACB | |
| SCHEMBL2228610 | 0.83 | ATM (0.42) | HRH3EP300ATMACHESLC6A4 | |
| SCHEMBL15075275 | 0.81 | HRH3 (0.45) | HRH3ATMSLC6A4ACACB | |
| SCHEMBL27866561 | 0.80 | EP300 (0.63) | EP300 | |
| SCHEMBL23012782 | 0.80 | ATM (0.42) | HRH3EP300ATMSLC6A4CHRM2 | |
| SCHEMBL429671 | 0.80 | LOXL2 (0.51) | HRH3NCF1SLC6A4CHRM2CHRM1 | |
| SCHEMBL30578250 | 0.80 | LOXL2 (0.51) | HRH3NCF1SLC6A4CHRM2CHRM1 | |
| SCHEMBL24493078 | 0.78 | HSD11B1 (0.53) | HRH3ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745278-A | Enzyme inhibitors | 卡尔维斯塔制药有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022118016-A2 | ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2022-06-09 | — | — | WO | disclosed |