Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | RAC2 | P15153 | 1/20 | 0.34 |
| ▸ | RAC3 | P60763 | 1/20 | 0.34 |
| ▸ | CDC42 | P60953 | 1/20 | 0.34 |
| ▸ | RAC1 | P63000 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24492899 | 0.97 | ATM (0.46) | ATML3MBTL1KDM4EPTGER4NPY5R | |
| SCHEMBL16231279 | 0.91 | ATM (0.45) | ATML3MBTL1KDM4EPTGER4NPY5R | |
| SCHEMBL24492782 | 0.90 | ATM (0.42) | ATML3MBTL1KDM4EPTGER4NPY5R | |
| SCHEMBL17227984 | 0.89 | L3MBTL1 (0.55) | ATML3MBTL1KDM4EPTGER4NPY5R | |
| SCHEMBL13759995 | 0.89 | L3MBTL1 (0.62) | ATML3MBTL1KDM4EPTGER4NPY5R | |
| SCHEMBL24492823 | 0.88 | ATM (0.39) | ATML3MBTL1KDM4EKMT2AMAPT | |
| SCHEMBL24493057 | 0.88 | L3MBTL1 (0.47) | ATML3MBTL1KDM4EKMT2AMAPT | |
| SCHEMBL24493054 | 0.87 | ATM (0.44) | ATML3MBTL1KDM4EDHFRCYP2A6 | |
| SCHEMBL18020714 | 0.87 | L3MBTL1 (0.60) | ATML3MBTL1KDM4EPTGER4NPY5R | |
| SCHEMBL18020705 | 0.87 | L3MBTL1 (0.60) | ATML3MBTL1KDM4EPTGER4NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177454-A1 | TRISUBSTITUTED BENZENE COMPOUND HAVING NITROGEN-CONTAINING HETERO RING IN MOLECULAR TERMINUS AND ORGANIC ELECTROLUMINESCENCE ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177454-A1 | TRISUBSTITUTED BENZENE COMPOUND HAVING NITROGEN-CONTAINING HETERO RING IN MOLECULAR TERMINUS AND ORGANIC ELECTROLUMINESCENCE ELEMENT | ETV6, LEF1, TEAD2 | ATM 3566/4885L3MBTL1 1418/4885KDM4E 688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.