Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2447956 | 1.00 | HPGD (0.69) | HPGDTSHRMAPTKMT2AMEN1 | |
| SCHEMBL2447953 | 1.00 | HPGD (0.69) | HPGDTSHRMAPTKMT2AMEN1 | |
| SCHEMBL29687081 | 1.00 | HPGD (0.69) | HPGDTSHRMAPTKMT2AMEN1 | |
| SCHEMBL17041014 | 0.81 | HPGD (1.00) | HPGDTSHRMAPTKMT2AMEN1 | |
| SCHEMBL3739640 | 0.80 | CYP1A1 (0.56) | HPGDMAPTKMT2AMEN1HTT | |
| SCHEMBL3739643 | 0.80 | CYP1A1 (0.56) | HPGDMAPTKMT2AMEN1HTT | |
| SCHEMBL20125076 | 0.80 | ACHE (0.50) | HPGDTSHRMAPTKMT2AMEN1 | |
| SCHEMBL16953295 | 0.79 | KDM4E (0.51) | HPGDTSHRMAPTKMT2AMEN1 | |
| SCHEMBL4285039 | 0.79 | KDM4E (0.48) | HPGDTSHRMAPTKMT2AMEN1 | |
| SCHEMBL30977632 | 0.79 | KMT2A (0.46) | HPGDTSHRMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507332-A | Octahydroisoquinolinyl derivatives | UCB生物制药有限责任公司 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022117678-A1 | OCTAHYDROISOQUINOLINYL DERIVATIVES | UCB Biopharma SRL (BE) | 2022-06-09 | — | — | WO | disclosed |