Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96202 | 0.85 | LMNA (0.50) | ACHELMNAALDH1A1MAPTCYP3A4 | |
| SCHEMBL3739640 | 0.81 | CYP1A1 (0.56) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL13622498 | 0.81 | ALDH1A1 (0.50) | ACHELMNAALDH1A1MAPTCYP3A4 | |
| SCHEMBL3739643 | 0.81 | CYP1A1 (0.56) | LMNAALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL24495458 | 0.80 | HPGD (0.69) | LMNAALDH1A1MAPTCYP3A4NPC1 | |
| SCHEMBL14041149 | 0.80 | HPGD (0.44) | LMNAALDH1A1MAPTCYP3A4NPC1 | |
| SCHEMBL2447953 | 0.80 | HPGD (0.69) | LMNAALDH1A1MAPTCYP3A4NPC1 | |
| SCHEMBL29687081 | 0.80 | HPGD (0.69) | LMNAALDH1A1MAPTCYP3A4NPC1 | |
| SCHEMBL31277402 | 0.80 | HPGD (0.69) | LMNAALDH1A1MAPTCYP3A4NPC1 | |
| SCHEMBL31277569 | 0.80 | HPGD (0.69) | LMNAALDH1A1MAPTCYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |