Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 3/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24501908 | 1.00 | TP53 (0.33) | TP53HBBSMN1; SMN2CPB1CPB2 | |
| SCHEMBL24496393 | 1.00 | TP53 (0.33) | TP53HBBSMN1; SMN2CPB1CPB2 | |
| SCHEMBL24936211 | 0.83 | KDM4C (0.48) | KDM4C | |
| SCHEMBL28853291 | 0.77 | TP53 (0.36) | TP53HBBSMN1; SMN2KDM4C | |
| SCHEMBL24501677 | 0.77 | TP53 (0.36) | TP53HBBSMN1; SMN2KDM4C | |
| SCHEMBL22185811 | 0.73 | KDM2B (0.49) | CPB1CPB2KDM4C | |
| SCHEMBL10081271 | 0.72 | CPB2 (0.41) | CPB1CPB2 | |
| SCHEMBL25581832 | 0.72 | CPB2 (0.54) | CPB1CPB2 | |
| SCHEMBL12710071 | 0.69 | KDM5A (0.39) | CPB1CPB2 | |
| SCHEMBL24495990 | 0.68 | CPB2 (0.40) | CPB1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120353-A1 | TEAD INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |
| WO-2022120354-A1 | TEAD INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |