Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | CASP7 | P55210 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24496393 | 0.83 | TP53 (0.33) | KDM4C | |
| SCHEMBL24496052 | 0.83 | TP53 (0.33) | KDM4C | |
| SCHEMBL24501908 | 0.83 | TP53 (0.33) | KDM4C | |
| Hydrochloric Acid SCHEMBL23389288 | 0.77 | KDM4C (0.50) | KDM4CWDR5ALDH1A1TSHRCYP1A2 | |
| Hydrochloric Acid SCHEMBL23389291 | 0.77 | KDM4C (0.50) | KDM4CWDR5ALDH1A1TSHRCYP1A2 | |
| SCHEMBL23389314 | 0.72 | KDM4C (0.49) | KDM4CWDR5ALDH1A1TSHRCYP1A2 | |
| SCHEMBL25617367 | 0.71 | KDM4E (0.40) | ALDH1A1TSHRCYP1A2CYP2C19KMT2A | |
| SCHEMBL25859573 | 0.71 | KDM4E (0.40) | ALDH1A1TSHRCYP1A2CYP2C19KMT2A | |
| SCHEMBL22185811 | 0.71 | KDM2B (0.49) | KDM4C | |
| SCHEMBL12090058 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022304-A1 | WDR5-MYC INHIBITORS | VANDERBILT UNIVERSITY | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230022304-A1 | WDR5-MYC INHIBITORS | MYC, WDR5, MYCBP | KDM4C 1517/4885WDR5 2/4885ALDH1A1 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.