Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28951034 | 1.00 | ALDH1A1 (0.48) | ALDH1A1PPARASMN1; SMN2LMNAKMT2A | |
| SCHEMBL28951011 | 1.00 | ALDH1A1 (0.48) | ALDH1A1PPARASMN1; SMN2LMNAKMT2A | |
| SCHEMBL22425939 | 0.84 | PPARA (0.47) | ALDH1A1PPARALMNAGAAHTT | |
| SCHEMBL22425737 | 0.84 | PPARA (0.47) | ALDH1A1PPARALMNAGAAHTT | |
| SCHEMBL22425744 | 0.84 | PPARA (0.47) | ALDH1A1PPARALMNAGAAHTT | |
| SCHEMBL22412070 | 0.83 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL31172077 | 0.83 | SMN1; SMN2 (0.52) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL22412005 | 0.82 | MTNR1A (0.38) | ALDH1A1LMNAGAAHTTMAPT | |
| SCHEMBL22411916 | 0.82 | PPARA (0.37) | ALDH1A1PPARAKMT2AMEN1PPARG | |
| SCHEMBL24496961 | 0.82 | PPARA (0.37) | ALDH1A1PPARASMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591351-B | Polycyclic compound and preparation method and application thereof | 成都科岭源医药技术有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022117090-A1 | POLYCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 成都科岭源医药技术有限公司 | 2022-06-09 | — | — | WO | disclosed |
| CN-114591351-A | Polycyclic compound and preparation method and application thereof | 成都科岭源医药技术有限公司 | 2022-06-07 | — | — | CN | disclosed |