Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.40 |
| ▸ | PGR | P06401 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.40 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23051121 | 0.89 | TDP1 (0.66) | TDP1LMNAHSD17B10L3MBTL1KMT2A | |
| SCHEMBL24497311 | 0.84 | MAPK1 (0.55) | TDP1LMNAHSD17B10L3MBTL1KMT2A | |
| SCHEMBL25938280 | 0.78 | LMNA (0.58) | TDP1LMNAHSD17B10KMT2AKDM4E | |
| SCHEMBL11371552 | 0.76 | TDP1 (0.61) | TDP1LMNAHSD17B10L3MBTL1KMT2A | |
| SCHEMBL11371549 | 0.76 | TDP1 (0.61) | TDP1LMNAHSD17B10L3MBTL1KMT2A | |
| SCHEMBL11183181 | 0.76 | TDP1 (0.68) | TDP1LMNAHSD17B10L3MBTL1KMT2A | |
| SCHEMBL11183173 | 0.76 | TDP1 (0.68) | TDP1LMNAHSD17B10L3MBTL1KMT2A | |
| SCHEMBL8867984 | 0.76 | TDP1 (0.68) | TDP1LMNAHSD17B10L3MBTL1KMT2A | |
| SCHEMBL8867974 | 0.76 | TDP1 (0.68) | TDP1LMNAHSD17B10L3MBTL1KMT2A | |
| SCHEMBL10735409 | 0.76 | LMNA (0.67) | TDP1LMNAHSD17B10L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177947-A1 | Compounds to Identify Beta-Lactamases, and Methods of Use Thereof | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177947-A1 | Compounds to Identify Beta-Lactamases, and Methods of Use Thereof | GUSB, GLB1, MGAM | TDP1 1470/4885LMNA 403/4885HSD17B10 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.