SCHEMBL2449735

SCHEMBL2449735

C=COC(C)Oc1ccc(O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 3/20 0.38
KMT2A Q03164 3/20 0.38
ESR1 P03372 2/20 0.38
MEN1 O00255 2/20 0.38
LTA4H P09960 3/20 0.36
PDCD1 Q15116 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
TTR P02766 2/20 0.34
CYP1A1 P04798 2/20 0.34
ALOX5 P09917 2/20 0.34
PTGS1 P23219 2/20 0.34
PTGS2 P35354 2/20 0.34
CYP1B1 Q16678 2/20 0.34
KDM4E B2RXH2 1/20 0.34
NPC1 O15118 1/20 0.34
ABL1 P00519 1/20 0.34
ABCB1 P08183 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
BCR P11274 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2454359 0.95 ESR2 (0.46) ESR2KMT2AESR1MEN1LTA4H
SCHEMBL2447906 0.92 CYP1A1 (0.47) KMT2AESR1MEN1LTA4HTTR
SCHEMBL1344967 0.90 ALDH1A3 (0.39) KMT2AKDM4EGAAALDH1A3
SCHEMBL2449212 0.84 KMT2A (0.40) ESR2KMT2AESR1MEN1NPC1
SCHEMBL3958244 0.84 CYP1A2 (0.39) ESR2KMT2AGAAMAPTALDH1A3
SCHEMBL2960693 0.82 ACHE (0.38) KMT2AMEN1KDM4EMAPTALDH1A3
SCHEMBL9557952 0.82 ALDH1A3 (0.34) ALDH1A3
SCHEMBL11788149 0.82 CA1 (0.44) ESR1TTRCYP1A1ALOX5PTGS2
SCHEMBL1477040 0.81 ESR2 (0.50) ESR2KMT2AESR1MEN1LTA4H
SCHEMBL6115215 0.81 ALDH1A3 (0.33) ALDH1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1422255-B1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY NIPPON OIL CORP (JP) 2011-09-28 EP disclosed
US-20100208182-A1 METHOD FOR MANUFACTURING OPTICAL FILM NIPPON OIL CORPORATION (JP) 2010-08-19 US disclosed
EP-2202546-A1 METHOD FOR PRODUCING OPTICAL FILM Nippon Oil Corporation (JP) 2010-06-30 EP disclosed
US-6894141-B2 Main chain type liquid crystalline polyester, liquid crystalline composition, method for producing liquid crystal film and optical film, and display having optical film NIPPON OIL CORPORATION (JP) 2005-05-17 US disclosed
US-20040171788-A1 Main chain type liquid crystal polyester, liquid crystalline composition, method for producing liquid crystal film, optical film and display NOBLE VENTURE FINANCE I LIMITED (GB) 2004-09-02 US disclosed
EP-1422255-A1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY Nippon Oil Corporation (JP) 2004-05-26 EP disclosed