Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 5/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.32 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.32 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.32 |
| ▸ | NPM1 | P06748 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26544477 | 0.86 | POLQ (0.34) | TYK2POLQHSD11B1 | |
| SCHEMBL24497510 | 0.80 | TYK2 (0.43) | TYK2CYP19A1JAK2JAK3PTK2 | |
| SCHEMBL29686281 | 0.79 | TYK2 (0.42) | TYK2CYP19A1JAK2JAK3PTK2 | |
| SCHEMBL24498229 | 0.79 | TYK2 (0.40) | TYK2CYP19A1JAK2JAK3PTK2 | |
| SCHEMBL20093009 | 0.79 | TYK2 (0.42) | TYK2CYP19A1JAK2JAK3PTK2 | |
| SCHEMBL26517347 | 0.78 | TYK2 (0.39) | TYK2CYP19A1POLQJAK2JAK3 | |
| SCHEMBL24498566 | 0.77 | TYK2 (0.39) | TYK2CYP19A1HSD11B1JAK2JAK3 | |
| SCHEMBL24497497 | 0.76 | NPSR1 (0.37) | TYK2CYP19A1PTK2KMT2AMEN1 | |
| SCHEMBL20230844 | 0.75 | GAA (0.40) | TYK2CYP19A1KMT2AMEN1 | |
| SCHEMBL29739965 | 0.74 | CYP19A1 (0.45) | TYK2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |