SCHEMBL26517347

SCHEMBL26517347

CCc1ccc(C2CC2)cc1N(C)S(C)(=O)=O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TYK2 P29597 5/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
POLQ O75417 1/20 0.36
DRD2 P14416 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
CYP19A1 P11511 5/20 0.34
NR1D1 P20393 1/20 0.34
JAK2 O60674 2/20 0.33
JAK3 P52333 2/20 0.33
PTK2 Q05397 2/20 0.33
PER2 O15055 1/20 0.32
CRY1 Q16526 1/20 0.32
CRY2 Q49AN0 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SPHK1 Q9NYA1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20155672 0.94 TYK2 (0.36) TYK2MEN1KMT2ADRD2SIGMAR1
SCHEMBL26517467 0.88 POLQ (0.36) TYK2POLQDRD2SIGMAR1NR1D1
SCHEMBL24497510 0.81 TYK2 (0.43) TYK2MEN1KMT2ACYP19A1JAK2
SCHEMBL24497615 0.80 TYK2 (0.46) TYK2JAK2JAK3PTK2
SCHEMBL20093009 0.80 TYK2 (0.42) TYK2KMT2ACYP19A1JAK2JAK3
SCHEMBL24498229 0.80 TYK2 (0.40) TYK2KMT2ACYP19A1JAK2JAK3
SCHEMBL29686281 0.80 TYK2 (0.42) TYK2KMT2ACYP19A1JAK2JAK3
SCHEMBL24497698 0.78 TYK2 (0.39) TYK2MEN1KMT2APOLQCYP19A1
SCHEMBL24498566 0.78 TYK2 (0.39) TYK2CYP19A1NR1D1JAK2JAK3
SCHEMBL20230844 0.76 GAA (0.40) TYK2MEN1KMT2ACYP19A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257587-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Shenzhen Chipscreen Biosciences Co., Ltd. (CN) 2023-10-11 EP disclosed