SCHEMBL24497703

SCHEMBL24497703

COc1c(C)cccc1-c1cnc(C(C)C)cn1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OXTR P30559 5/20 0.39
AVPR2 P30518 1/20 0.38
TLR8 Q9NR97 1/20 0.38
ALOX5AP P20292 7/20 0.37
FEN1 P39748 7/20 0.37
AVPR1A P37288 2/20 0.36
SCN4A P35499 3/20 0.35
LMNA P02545 2/20 0.35
SCN1A P35498 2/20 0.35
SCN5A Q14524 2/20 0.35
SCN9A Q15858 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
KCNK3 O14649 1/20 0.35
CACNA1F O60840 1/20 0.35
KCNK2 O95069 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29686208 0.84 FEN1 (0.44) ALOX5APFEN1PDCD1CD274
SCHEMBL24498032 0.84 FEN1 (0.44) ALOX5APFEN1PDCD1CD274
SCHEMBL24497542 0.81 TYK2 (0.42) OXTRAVPR2TLR8ALOX5APFEN1
SCHEMBL26124861 0.79 TYK2 (0.43) OXTRAVPR2ALOX5APFEN1AVPR1A
SCHEMBL26513797 0.78 FEN1 (0.35) OXTRAVPR2ALOX5APFEN1AVPR1A
SCHEMBL28838963 0.77 ADORA3 (0.37) OXTRAVPR2ALOX5APFEN1LMNA
SCHEMBL17194890 0.74 MAPK1 (0.43) TLR8CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL24497525 0.73 ALOX5AP (0.40) OXTRAVPR2ALOX5APFEN1CYP3A4
SCHEMBL26512732 0.73 KDM1A (0.41) OXTRTLR8ALOX5APFEN1SCN8A
SCHEMBL29739983 0.72 METAP1 (0.39) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257587-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Shenzhen Chipscreen Biosciences Co., Ltd. (CN) 2023-10-11 EP disclosed
WO-2022117016-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 深圳微芯生物科技股份有限公司 2022-06-09 WO disclosed