SCHEMBL24498237

SCHEMBL24498237

CCS(=O)(=O)N(C)c1cc(C2CC2)ccc1C(C)C

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR1D1 P20393 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
DRD2 P14416 4/20 0.33
SIGMAR1 Q99720 1/20 0.33
SPHK1 Q9NYA1 1/20 0.33
SLC6A4 P31645 1/20 0.33
DRD3 P35462 2/20 0.32
POLQ O75417 1/20 0.32
HSD11B1 P28845 1/20 0.31
CYP2C9 P11712 1/20 0.31
GRIA1 P42261 1/20 0.30
GRIA2 P42262 1/20 0.30
GRIA3 P42263 1/20 0.30
TYK2 P29597 2/20 0.30
TLR8 Q9NR97 2/20 0.30
TLR7 Q9NYK1 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24498566 0.86 TYK2 (0.39) NR1D1ALDH1A1HPGDHSD11B1GRIA2
SCHEMBL24497539 0.83 HSD11B1 (0.33) NR1D1ALDH1A1HPGDHSD11B1TYK2
SCHEMBL26517467 0.81 POLQ (0.36) NR1D1ALDH1A1DRD2SIGMAR1SPHK1
SCHEMBL24498147 0.81 GAA (0.35) NR1D1ALDH1A1DRD2SIGMAR1SPHK1
SCHEMBL20073679 0.81 TYK2 (0.36) ALDH1A1HPGDGRIA2TYK2
SCHEMBL24498549 0.80 CYP2C9 (0.35) NR1D1ALDH1A1DRD2SIGMAR1SPHK1
SCHEMBL24497524 0.80 PSEN1 (0.40) ALDH1A1HPGD
SCHEMBL24497546 0.78 AKR1B1 (0.43) ALDH1A1HPGD
SCHEMBL24497570 0.78 DRD2 (0.33) NR1D1DRD2SIGMAR1SPHK1SLC6A4
SCHEMBL26544477 0.78 POLQ (0.34) NR1D1ALDH1A1DRD2SIGMAR1SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4257587-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Shenzhen Chipscreen Biosciences Co., Ltd. (CN) 2023-10-11 EP disclosed
WO-2022117016-A1 HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 深圳微芯生物科技股份有限公司 2022-06-09 WO disclosed