Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.58 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.58 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.47 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28198916 | 0.84 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL8936715 | 0.81 | CYP11B1 (0.58) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL9748629 | 0.81 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL30474205 | 0.80 | CYP11B1 (0.57) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL5306950 | 0.78 | CYP11B1 (0.58) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL27217139 | 0.77 | CYP11B1 (0.65) | CYP19A1CYP11B1CYP11B2TBXAS1CYP1A2 | |
| SCHEMBL4858800 | 0.75 | MEN1 (0.60) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL570342 | 0.74 | CYP11B1 (1.00) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL11232352 | 0.74 | CYP19A1 (0.57) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL13105206 | 0.73 | CYP11B1 (0.58) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177490-A1 | COMPOUNDS HAVING BOTH EFFECTS OF BET BROMODOMAIN PROTEIN INHIBITION AND PD-L1 GENE REGULATION | MEDSHINE DISCOVERY INC. (CN) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177490-A1 | COMPOUNDS HAVING BOTH EFFECTS OF BET BROMODOMAIN PROTEIN INHIBITION AND PD-L1 GENE REGULATION | BET1, BRD4, BRD3 | CYP19A1 4182/4885CYP11B1 3110/4885CYP11B2 3293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.