Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936715 | 0.83 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL9748629 | 0.83 | CYP19A1 (0.62) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL28198916 | 0.83 | CYP19A1 (0.62) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL5306950 | 0.80 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL24500044 | 0.80 | CYP19A1 (0.58) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL20622756 | 0.79 | CYP11B1 (0.66) | CYP11B1CYP11B2CYP19A1TBXAS1POLB | |
| SCHEMBL4858800 | 0.77 | MEN1 (0.60) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL13105206 | 0.76 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| SCHEMBL15125631 | 0.75 | DHFR (0.49) | CYP11B1CYP11B2CYP19A1TBXAS1POLB | |
| SCHEMBL11701986 | 0.74 | CYP2C9 (0.55) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250109148-A1 | HETEROCYCLIC GLP-1 AGONISTS | SHANGHAI SHOUTI BIOTECHNOLOGY CO., LTD. (CN) | 2025-04-03 | — | — | US | disclosed |
| CN-119343339-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2025-01-21 | — | — | CN | disclosed |
| EP-4469444-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2023138684-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO , INC. (US) | 2023-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250109148-A1 | HETEROCYCLIC GLP-1 AGONISTS | GLP1R, GIPR, GCGR | CYP11B1 826/4885CYP11B2 1232/4885CYP19A1 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.