Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24501399 | 1.00 | POLB (0.31) | POLB | |
| SCHEMBL24501402 | 1.00 | POLB (0.31) | POLB | |
| SCHEMBL29695012 | 1.00 | POLB (0.31) | POLB | |
| SCHEMBL22717781 | 0.78 | POLB (0.40) | POLB | |
| SCHEMBL24501285 | 0.78 | POLB (0.35) | POLB | |
| SCHEMBL24500977 | 0.76 | ALDH1A1 (0.35) | POLB | |
| SCHEMBL27294277 | 0.76 | ALDH1A1 (0.35) | POLB | |
| SCHEMBL24501660 | 0.76 | ALDH1A1 (0.35) | POLB | |
| SCHEMBL24501048 | 0.76 | ALDH1A1 (0.35) | POLB | |
| SCHEMBL29108134 | 0.75 | POLB (0.33) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022118210-A1 | SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2022-06-09 | — | — | WO | disclosed |