Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK1 | P51617 | 2/20 | 0.49 |
| ▸ | IRAK3 | Q9Y616 | 2/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.39 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.39 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29648313 | 1.00 | IRAK1 (0.49) | IRAK1IRAK3CRBNMEN1ALDH1A1 | |
| SCHEMBL30962345 | 0.92 | CRBN (0.46) | IRAK1IRAK3CRBNMEN1ALDH1A1 | |
| SCHEMBL29648286 | 0.86 | CRBN (0.54) | IRAK1IRAK3CRBNMEN1ALDH1A1 | |
| SCHEMBL24501060 | 0.86 | CRBN (0.54) | IRAK1IRAK3CRBNMEN1ALDH1A1 | |
| SCHEMBL29648377 | 0.84 | CRBN (0.67) | IRAK1IRAK3CRBNALDH1A1CCNC | |
| SCHEMBL22290046 | 0.84 | CRBN (0.67) | IRAK1IRAK3CRBNALDH1A1CCNC | |
| SCHEMBL24501729 | 0.84 | CRBN (0.67) | IRAK1IRAK3CRBNALDH1A1CCNC | |
| Hydrochloric Acid SCHEMBL31373761 | 0.83 | CRBN (0.66) | IRAK1IRAK3CRBNALDH1A1CCNC | |
| SCHEMBL24501045 | 0.83 | IRAK1 (0.53) | IRAK1IRAK3CRBNCCNCCDK8 | |
| SCHEMBL29648294 | 0.83 | IRAK1 (0.53) | IRAK1IRAK3CRBNCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |