Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.42 |
| ▸ | IRAK3 | Q9Y616 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29648313 | 0.92 | IRAK1 (0.49) | CRBNMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL24501659 | 0.92 | IRAK1 (0.49) | CRBNMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL29648286 | 0.87 | CRBN (0.54) | CRBNMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL24501060 | 0.87 | CRBN (0.54) | CRBNMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL30320020 | 0.83 | CRBN (0.70) | CRBNALDH1A1IRAK1IRAK3AR | |
| SCHEMBL20231895 | 0.83 | CRBN (0.70) | CRBNALDH1A1IRAK1IRAK3AR | |
| SCHEMBL29250882 | 0.83 | CRBN (0.70) | CRBNALDH1A1IRAK1IRAK3AR | |
| SCHEMBL26139423 | 0.82 | CRBN (0.47) | CRBNMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL30042811 | 0.82 | CRBN (0.47) | CRBNMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL30962354 | 0.82 | IRAK1 (0.47) | CRBNIRAK1IRAK3ARCDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4633732-A1 | HETEROCYCLIC COMPOUNDS TARGETING THE NUDT5 PROTEIN | Oxford University Innovation Limited (GB) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024127022-A1 | HETEROCYCLIC COMPOUNDS TARGETING THE NUDT5 PROTEIN | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2024-06-20 | — | — | WO | disclosed |