Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29300354 | 1.00 | TSHR (0.36) | TSHRCYP3A4HSD17B10 | |
| SCHEMBL21126317 | 1.00 | TSHR (0.36) | TSHRCYP3A4HSD17B10 | |
| SCHEMBL22268676 | 0.92 | LMNA (0.34) | TSHRCYP3A4HSD17B10 | |
| SCHEMBL19543335 | 0.91 | GABBR2 (0.30) | — | |
| SCHEMBL28580084 | 0.89 | GABBR2 (0.31) | — | |
| SCHEMBL22663332 | 0.86 | HSD17B10 (0.42) | TSHRHSD17B10 | |
| SCHEMBL9750949 | 0.86 | TSHR (0.46) | TSHRHSD17B10 | |
| SCHEMBL14307363 | 0.84 | CYP3A4 (0.33) | CYP3A4 | |
| SCHEMBL26020904 | 0.84 | CYP3A4 (0.33) | CYP3A4 | |
| SCHEMBL10821337 | 0.82 | CYP3A4 (0.34) | CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |