Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19824269 | 0.84 | GRIA1 (0.56) | GRIA1ALDH1A1TSHRNPY5RGRIA4 | |
| SCHEMBL7039391 | 0.84 | GRIA1 (1.00) | GRIA1ALDH1A1NPY5RSMN1; SMN2GRIA4 | |
| SCHEMBL7042049 | 0.84 | GRIA1 (1.00) | GRIA1ALDH1A1NPY5RSMN1; SMN2GRIA4 | |
| SCHEMBL7109326 | 0.84 | GRIA1 (1.00) | GRIA1ALDH1A1NPY5RSMN1; SMN2GRIA4 | |
| SCHEMBL20734509 | 0.76 | GRIA1 (0.83) | GRIA1 | |
| SCHEMBL24735803 | 0.76 | GRIA1 (0.83) | GRIA1 | |
| SCHEMBL13959008 | 0.76 | GRIA1 (0.83) | GRIA1 | |
| SCHEMBL19824268 | 0.75 | GRIA1 (0.46) | GRIA1ALDH1A1NPY5RGRIA4 | |
| SCHEMBL13616169 | 0.75 | ALDH1A1 (0.50) | GRIA1ALDH1A1TSHRSMN1; SMN2HTT | |
| SCHEMBL13105698 | 0.75 | GRIA1 (0.79) | GRIA1ALDH1A1NPY5RGRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |