Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | S100A9 | P06702 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22718045 | 0.79 | ALDH1A1 (0.58) | HTTKMT2AALDH1A1S100A9GAA | |
| SCHEMBL29267262 | 0.79 | PARG (0.44) | HTTKMT2A | |
| SCHEMBL29267304 | 0.77 | HTT (0.50) | HTTKMT2ANPC1ALDH1A1CA1 | |
| SCHEMBL31275351 | 0.77 | HTT (0.50) | HTTKMT2AALDH1A1CA1CA2 | |
| SCHEMBL1370997 | 0.77 | HTT (0.50) | HTTKMT2AALDH1A1CA1CA2 | |
| SCHEMBL11682482 | 0.76 | CA1 (0.59) | HTTALDH1A1CA1CA2CA3 | |
| SCHEMBL28645824 | 0.75 | HTT (0.48) | HTTKMT2ANPC1ALDH1A1CA1 | |
| Bromide SCHEMBL7392827 | 0.75 | HTT (0.48) | HTTKMT2AALDH1A1CA1CA2 | |
| SCHEMBL29045347 | 0.75 | HTT (0.48) | HTTKMT2AALDH1A1CA1CA2 | |
| SCHEMBL7392823 | 0.74 | HTT (0.47) | HTTKMT2ANPC1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120355-A1 | TEAD DEGRADERS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-09 | — | — | WO | disclosed |