Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 19/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30713210 | 0.83 | ALDH1A1 (0.51) | PARGHTTKMT2A | |
| SCHEMBL29277626 | 0.83 | ALDH1A1 (0.51) | PARGHTTKMT2A | |
| SCHEMBL29277605 | 0.80 | PARG (0.45) | PARGHTTKMT2A | |
| SCHEMBL24501924 | 0.79 | HTT (0.46) | HTTKMT2A | |
| SCHEMBL31468146 | 0.73 | PARG (0.43) | PARG | |
| SCHEMBL29267304 | 0.70 | HTT (0.50) | HTTKMT2A | |
| SCHEMBL1370997 | 0.70 | HTT (0.50) | HTTKMT2A | |
| SCHEMBL31275351 | 0.70 | HTT (0.50) | HTTKMT2A | |
| SCHEMBL30357530 | 0.69 | PARG (0.44) | PARG | |
| SCHEMBL19770706 | 0.69 | PARG (0.56) | PARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4413001-A1 | PARG INHIBITORY COMPOUNDS | FoRx Therapeutics AG (CH) | 2024-08-14 | — | — | EP | disclosed |
| CN-118055934-A | PARG inhibitory compounds | 福克斯治疗股份公司 | 2024-05-17 | — | — | CN | disclosed |
| WO-2023057389-A1 | PARG INHIBITORY COMPOUNDS | FORX THERAPEUTICS AG (CH) | 2023-04-13 | — | — | WO | disclosed |