Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422924 | 0.86 | ELANE (0.50) | ELANEALDH1A1MAPTTDP1POLB | |
| SCHEMBL9018645 | 0.86 | NPC1 (0.54) | ELANEALDH1A1MAPTTDP1POLB | |
| SCHEMBL161364 | 0.85 | ALDH1A1 (0.50) | ELANEALDH1A1MAPTTDP1LMNA | |
| SCHEMBL27733966 | 0.83 | ELANE (0.47) | ELANEALDH1A1MAPTTDP1POLB | |
| SCHEMBL28776762 | 0.81 | RAB9A (0.50) | ELANEALDH1A1MAPTTDP1LMNA | |
| SCHEMBL28770867 | 0.81 | ELANE (0.46) | ELANEALDH1A1MAPTTDP1POLB | |
| SCHEMBL4644345 | 0.80 | ELANE (0.45) | ELANEALDH1A1MAPTTDP1POLB | |
| SCHEMBL5143592 | 0.79 | TDP1 (0.57) | ALDH1A1TDP1POLBLMNATSHR | |
| SCHEMBL20100442 | 0.79 | ATM (0.55) | ELANEALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL28450130 | 0.79 | KMT2A (0.49) | ALDH1A1MAPTTDP1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220181140-A1 | SELECTIVE LIQUIPHOBIC SURFACE MODIFICATION OF SUBSTRATES | BREWER SCIENCE, INC. | 2022-06-09 | — | — | US | disclosed |