Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.61 |
| ▸ | HTR2A | P28223 | 4/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL951642 | 0.99 | HTR6 (0.60) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL950399 | 0.90 | HTR6 (0.51) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL949296 | 0.89 | HTR6 (0.50) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL2447533 | 0.88 | HTR6 (0.58) | HTR6HTR2AHTR1ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL949561 | 0.87 | HTR6 (0.57) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL952720 | 0.86 | HTR6 (0.55) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL948371 | 0.86 | HTR6 (0.48) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL949399 | 0.82 | HTR6 (0.60) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL4688092 | 0.81 | HTR6 (0.56) | HTR6HTR2AHTR1ADRD2HTR7 | |
| SCHEMBL4648947 | 0.81 | HTR6 (0.58) | HTR6HTR2AHTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679351-B | Quinoline compounds suitable for treating didorders that respond to modulation of the serotonin 5-ht6 receptor | ABBVIE GMBH & CO KG | 2015-01-07 | — | — | CN | claimed |
| EP-2139880-B1 | QUINOLINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR | ABBOTT GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | claimed |