Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17302214 | 0.80 | CA9 (0.50) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL24504058 | 0.76 | DYRK2 (0.44) | ALDH1A1MAPTKDM4ELMNAADAM17 | |
| SCHEMBL17302215 | 0.72 | CFTR (0.51) | ALDH1A1MAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL19096574 | 0.68 | CA9 (0.51) | POLBALDH1A1MAPTSMN1; SMN2GSK3B | |
| SCHEMBL19096526 | 0.67 | FAAH (0.58) | POLBALDH1A1MAPTSMN1; SMN2PIM1 | |
| SCHEMBL19096521 | 0.66 | FAAH (0.58) | ALDH1A1MAPTSMN1; SMN2PIM1DYRK2 | |
| SCHEMBL19096261 | 0.66 | FAAH (0.58) | ALDH1A1MAPTSMN1; SMN2PIM1DYRK2 | |
| SCHEMBL19096569 | 0.65 | MEN1 (0.54) | POLBALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL19120876 | 0.65 | DYRK1A (0.41) | POLBALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL17295338 | 0.64 | FAAH (0.54) | ALDH1A1MAPTSMN1; SMN2PIM1DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4011879-A1 | THIAZOLIDINONE COMPOUNDS AND THEIR USE IN THE TREATMENT OF PSYCHIATRIC OR NEUROLOGICAL DISORDERS AND INFLAMMATION, IN PARTICULAR NEUROINFLAMMATION | Universität Bern (CH) | 2022-06-15 | — | — | EP | disclosed |