SCHEMBL24504159

SCHEMBL24504159

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)C(CC(=O)N1CCCCC1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)N)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 2/20 0.49
▸ OPRD1 P41143 6/20 0.47
▸ NTSR1 P30989 6/20 0.47
▸ NTSR2 O95665 4/20 0.47
▸ SORT1 Q99523 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24504160 0.90 NTSR1 (0.48) F2OPRD1NTSR1NTSR2SORT1
SCHEMBL24516989 0.89 F2 (0.56) F2OPRD1NTSR1NTSR2
SCHEMBL24504179 0.89 F2 (0.54) F2OPRD1NTSR1NTSR2
SCHEMBL24517136 0.88 NTSR1 (0.49) F2OPRD1NTSR1NTSR2SORT1
SCHEMBL24517139 0.86 OPRD1 (0.54) F2OPRD1NTSR1NTSR2
SCHEMBL16847816 0.83 F2 (0.52) F2OPRD1NTSR1NTSR2
SCHEMBL9058846 0.81 OPRD1 (0.56) F2OPRD1NTSR1NTSR2SORT1
SCHEMBL29658852 0.81 F2 (0.55) F2OPRD1
SCHEMBL31253371 0.81 OPRD1 (0.52) F2OPRD1NTSR1NTSR2
SCHEMBL30547470 0.80 OPRD1 (0.54) OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692007-B2 Amino deprotection using 3-(diethylamino)propylamine Alma Mater Studiorum—Università di Bologna (IT) 2023-07-04 — — US disclosed
US-11692007-B2 Amino deprotection using 3-(diethylamino)propylamine Alma Mater Studiorum—Università di Bologna (IT) 2023-07-04 — — US disclosed
US-20220185842-A1 AMINO DEPROTECTION USING 3-(DIETHYLAMINO)PROPYLAMINE Alma Mater Studiorum - Università di Bologna (IT) 2022-06-16 — — US disclosed
EP-4011901-A1 METHOD FOR THE FMOC GROUP CLEAVAGE Fresenius Kabi iPSUM S.r.l. (IT) 2022-06-15 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220185842-A1 AMINO DEPROTECTION USING 3-(DIETHYLAMINO)PROPYLAMINE PEPD, ANPEP, DNPEP F2 1522/4885OPRD1 1918/4885NTSR1 168/4885
US-11692007-B2 Amino deprotection using 3-(diethylamino)propylamine PEPD, ANPEP, DNPEP F2 1522/4885OPRD1 1918/4885NTSR1 168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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