Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898896 | 0.94 | KDM4E (0.67) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL8173437 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1MAPTPKMHTR3E | |
| SCHEMBL11537322 | 0.80 | MAPT (0.53) | KDM4EALDH1A1MAPTPKMHTR3E | |
| SCHEMBL10169302 | 0.79 | MAPT (0.67) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL1742772 | 0.79 | OGA (0.44) | ALDH1A1MAPTHRH3HTR3ASMN1; SMN2 | |
| SCHEMBL29998630 | 0.78 | HTR3E (0.70) | KDM4EALDH1A1MAPTHTR3EHTR3B | |
| SCHEMBL870704 | 0.78 | HTR3E (0.70) | KDM4EALDH1A1MAPTHTR3EHTR3B | |
| SCHEMBL1744089 | 0.78 | CNR2 (0.49) | KDM4EHRH3ACVR1 | |
| SCHEMBL30894944 | 0.77 | TLR9 (0.43) | KDM4EALDH1A1MAPTPKMHRH3 | |
| SCHEMBL81911 | 0.77 | MAPT (0.69) | KDM4EALDH1A1MAPTPKMHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4011874-A1 | SUBSTITUTED PYRAZOLO PIPERIDINE CARBOXYLIC ACIDS | Bayer Aktiengesellschaft (DE) | 2022-06-15 | — | — | EP | disclosed |