SCHEMBL29998630

SCHEMBL29998630

Clc1ccc(N2CCN(c3ccc(Cl)cc3)CC2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 1/20 0.70
HTR3B O95264 1/20 0.70
ADRB1 P08588 1/20 0.70
HTR3A P46098 1/20 0.70
HTR3D Q70Z44 1/20 0.70
HTR3C Q8WXA8 1/20 0.70
SIGMAR1 Q99720 1/20 0.70
CHIA Q9BZP6 1/20 0.63
DRD4 P21917 1/20 0.61
AKR1C3 P42330 4/20 0.59
ALDH1A1 P00352 4/20 0.59
LMNA P02545 2/20 0.59
HPGD P15428 1/20 0.59
HTT P42858 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
MAPT P10636 2/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
LTA4H P09960 2/20 0.55
GAA P10253 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL870704 1.00 HTR3E (0.70) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL24103508 0.89 SIGMAR1 (0.64) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL11771698 0.89 HTR3E (0.58) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL1822749 0.89 HTR3E (0.64) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL5539457 0.88 ME2 (0.63) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL21361448 0.88 HTR3E (0.57) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL11210729 0.88 CHIA (0.58) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL22815633 0.88 CHIA (0.58) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL7266357 0.88 CHIA (0.58) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL2056127 0.88 GAA (0.63) HTR3EHTR3BADRB1HTR3AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111362886-B Preparation method of posaconazole intermediate 1- (4-aminophenyl) -4- (4-hydroxyphenyl) piperazine 四川澄华生物科技有限公司 2023-05-16 CN claimed
WO-2025105341-A1 METAL PATTERNING MATERIAL, PENTAFLUOROSULFANYL COMPOUND, METAL PATTERNING THIN FILM, ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC APPARATUS, AND METAL PATTERN FORMING METHOD 東ソー株式会社 2025-05-22 WO disclosed
CN-111362886-B Preparation method of posaconazole intermediate 1- (4-aminophenyl) -4- (4-hydroxyphenyl) piperazine 四川澄华生物科技有限公司 2023-05-16 CN disclosed
CN-111362886-B Preparation method of posaconazole intermediate 1- (4-aminophenyl) -4- (4-hydroxyphenyl) piperazine 四川澄华生物科技有限公司 2023-05-16 CN disclosed
CN-113292514-B Piperazine derivative and organic photoelectric device comprising same 浙江华显光电科技有限公司 2022-11-15 CN disclosed