SCHEMBL2450469

SCHEMBL2450469

Oc1ccc(/C=C/c2ccc(OCC3CCO3)cc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.46
CHRNB2 P17787 2/20 0.43
CHRNB4 P30926 2/20 0.43
CHRNA3 P32297 2/20 0.43
CHRNA7 P36544 2/20 0.43
CHRNA4 P43681 2/20 0.43
NPC1 O15118 5/20 0.42
RAB9A P51151 5/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
MIF P14174 1/20 0.41
LMNA P02545 3/20 0.41
MAOB P27338 3/20 0.41
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA3 P07451 2/20 0.41
CA4 P22748 2/20 0.41
CA6 P23280 2/20 0.41
CA5A P35218 2/20 0.41
CA7 P43166 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2450470 1.00 HPGD (0.46) HPGDCHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL2449484 0.91 RAB9A (0.48) HPGDNPC1RAB9ASMN1; SMN2MIF
SCHEMBL21051376 0.91 RAB9A (0.48) HPGDNPC1RAB9ASMN1; SMN2MIF
SCHEMBL21051363 0.91 RAB9A (0.48) HPGDNPC1RAB9ASMN1; SMN2MIF
SCHEMBL2447063 0.88 TDP1 (0.54) HPGDCHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL2447060 0.88 TDP1 (0.54) HPGDCHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL2449880 0.86 PRKAB2 (0.46) HPGDCHRNB4CHRNA3NPC1RAB9A
SCHEMBL2449722 0.83 RAB9A (0.50) HPGDNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL2449725 0.83 RAB9A (0.50) HPGDNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL21051390 0.83 RAB9A (0.58) HPGDNPC1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006351-B1 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM NIPPON OIL CORP (JP) 2011-10-12 EP disclosed
EP-1422255-B1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY NIPPON OIL CORP (JP) 2011-09-28 EP disclosed
US-20100208182-A1 METHOD FOR MANUFACTURING OPTICAL FILM NIPPON OIL CORPORATION (JP) 2010-08-19 US disclosed
US-7763182-B2 Liquid crystalline composition with improved adhesivity, liquid crystal film comprising the composition, and liquid crystal display device equipped with the film NIPPON OIL CORPORATION (JP) 2010-07-27 US disclosed
EP-2202546-A1 METHOD FOR PRODUCING OPTICAL FILM Nippon Oil Corporation (JP) 2010-06-30 EP disclosed
US-20090208673-A1 Liquid Crystalline Composition with Improved Adhesivity, Liquid Crystal Film Comprising the Composition, and Liquid Crystal Display Device Equipped with the Film NIPPON OIL CORPORATION (JP) 2009-08-20 US disclosed
EP-2006351-A9 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM Nippon Oil Corporation (JP) 2009-07-01 EP disclosed
EP-2006351-A2 LIQUID-CRYSTALLINE COMPOSITION WITH IMPROVED ADHESION, LIQUID-CRYSTAL FILM COMPRISING THE COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT EMPLOYING THE FILM Nippon Oil Corporation (JP) 2008-12-24 EP disclosed
US-6894141-B2 Main chain type liquid crystalline polyester, liquid crystalline composition, method for producing liquid crystal film and optical film, and display having optical film NIPPON OIL CORPORATION (JP) 2005-05-17 US disclosed
US-20040171788-A1 Main chain type liquid crystal polyester, liquid crystalline composition, method for producing liquid crystal film, optical film and display NOBLE VENTURE FINANCE I LIMITED (GB) 2004-09-02 US disclosed
EP-1422255-A1 MAIN CHAIN TYPE LIQUID CRYSTAL POLYESTER LIQUID CRYSTALLINE COMPOSITION METHOD FOR PRODUCING LIQUID CRYSTAL FILM OPTICAL FILM AND DISPLAY Nippon Oil Corporation (JP) 2004-05-26 EP disclosed