Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | MAP3K12 | Q12852 | 2/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.42 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
| ▸ | CASP5 | P51878 | 1/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.41 |
| ▸ | QDPR | P09417 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24506927 | 0.87 | LRRK2 (0.56) | ADRB1LRRK2 | |
| SCHEMBL22458969 | 0.78 | PROKR1 (0.43) | ADRB1MAP3K12PROKR1HRH4LRRK2 | |
| Hydrochloric Acid SCHEMBL30476651 | 0.76 | CHRNA7 (0.45) | CASP1CASP4CASP5PLD1QDPR | |
| Hydrochloric Acid SCHEMBL25318678 | 0.76 | CHRNA7 (0.45) | CASP1CASP4CASP5PLD1QDPR | |
| SCHEMBL16795287 | 0.73 | HRH4 (0.65) | ADRB1HRH4PRKD3PRKD1PRKD2 | |
| SCHEMBL12975529 | 0.72 | QDPR (0.47) | MAP3K12QDPRHTR2CSLC18A3SIGMAR1 | |
| SCHEMBL5584524 | 0.72 | TLR7 (0.56) | QDPRHTR2CSLC18A3SIGMAR1 | |
| SCHEMBL31510721 | 0.72 | QDPR (0.56) | QDPRHTR2CSLC18A3SIGMAR1 | |
| SCHEMBL15535152 | 0.72 | MKNK1 (0.55) | MAP3K12HRH4QDPRHTR2CSLC18A3 | |
| SCHEMBL28306485 | 0.72 | TLR9 (0.52) | QDPRHTR2CSLC18A3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125925-A1 | COMPOSITIONS FOR TREATING DRY AGE-RELATED MACULAR DEGENERATION (AMD) | COGNITION THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |