Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL1834227 | 0.93 | CYP3A4 (0.58) | ALDH1A1CYP3A4L3MBTL1TSHRTDP1 | |
| Ethylene Glycol SCHEMBL33531 | 0.93 | CYP3A4 (0.58) | ALDH1A1CYP3A4L3MBTL1TSHRTDP1 | |
| SCHEMBL80432 | 0.93 | CYP3A4 (0.67) | ALDH1A1CYP3A4L3MBTL1TSHRTDP1 | |
| SCHEMBL23087841 | 0.91 | CYP3A4 (0.64) | ALDH1A1CYP3A4L3MBTL1TSHRTDP1 | |
| Calcium SCHEMBL10786160 | 0.91 | CYP3A4 (0.64) | ALDH1A1CYP3A4L3MBTL1TSHRTDP1 | |
| SCHEMBL18835723 | 0.91 | CYP3A4 (0.64) | ALDH1A1CYP3A4L3MBTL1TSHRTDP1 | |
| Magnesium SCHEMBL10786879 | 0.91 | CYP3A4 (0.64) | ALDH1A1CYP3A4L3MBTL1TSHRTDP1 | |
| Potassium SCHEMBL18260591 | 0.91 | CYP3A4 (0.64) | ALDH1A1CYP3A4L3MBTL1TSHRTDP1 | |
| Barium SCHEMBL10790747 | 0.91 | CYP3A4 (0.64) | ALDH1A1CYP3A4L3MBTL1TSHRTDP1 | |
| SCHEMBL288653 | 0.91 | CYP3A4 (0.64) | ALDH1A1CYP3A4L3MBTL1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237720-A1 | Method for Producing Dialkylphosphinic Acids and Esters and Salts Thereof by Means of Vinyl Compounds and Use Thereof | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-09-29 | — | — | US | disclosed |
| EP-1046431-B1 | Method for forming multi-layer paint film | KANSAI PAINT CO LTD (JP) | 2005-04-06 | — | — | EP | disclosed |
| US-6730203-B2 | COATING CATIONIC ELECTRODEPOSITION COMPOSITION CONTAINING BLOCKED POLYISOCYANATE AS CROSSLINKING AGENT TO FORM NON-CURED FILM, COATING WATER BASED INTERCOAT COATING COMPOSITION, ALUMINUM, TITANIUM OXIDE, HEAT CURING | KANSAI PAINT CO., LTD. (JP) | 2004-05-04 | — | — | US | disclosed |
| US-6645362-B2 | Applying a water based intermediate coat paint containing a block polyisocyanate compound as a crosslinking agent on an electrodeposition paint film surface without curing; heating to cure both paints | KANSAI PAINT CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| US-20020136919-A1 | Method for forming multi-layer paint film | TOMIZAKI YASUHIRO (JP) | 2002-09-26 | — | — | US | disclosed |
| US-20020104760-A1 | Method for forming multi-layer paint film | TOMIZAKI YASUHIRO (JP) | 2002-08-08 | — | — | US | disclosed |
| US-20020056642-A1 | Multi-layer coating film-forming method | KANSAI PAINT CO., LTD. (JP) | 2002-05-16 | — | — | US | disclosed |
| US-6375820-B1 | CURING BLOCK POLYISOCYANATE AS CROSSLINKING AGENT IN PRESENCE OF BASIC TIN COMPOUND CATALYST, BISMUTH COMPOUND AND OXYALKYLCARBOXYLIC ACID; ANTIPEELING AGENTS; CORROSION RESISTANCE; CATIONIC POLYMERS; POLYURETHANES | KANSAI PAINT CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| EP-1046431-A2 | Method for forming multi-layer paint film | KANSAI PAINT CO., LTD. (JP) | 2000-10-25 | — | — | EP | disclosed |
| EP-1027938-A1 | METHOD OF FORMING MULTILAYERED COATING FILM | KANSAI PAINT CO., LTD. (JP) | 2000-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020056642-A1 | Multi-layer coating film-forming method | TET1, PUF60, TET3 | MMP8 3842/4885ALDH1A1 405/4885CYP3A4 2083/4885 |
| US-20110237720-A1 | Method for Producing Dialkylphosphinic Acids and Esters and Salts Thereof by Means of Vinyl Compounds and Use Thereof | ACSL3, ACSL6, ACSL1 | MMP8 4366/4885ALDH1A1 1801/4885CYP3A4 2260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.