Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4914342 | 0.79 | GNAI3 (0.50) | GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL28215940 | 0.79 | GPR183 (0.49) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL19865695 | 0.78 | GNAI3 (0.53) | GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL22521105 | 0.78 | HRH2 (0.56) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL11063714 | 0.78 | GNAI3 (0.48) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL11871252 | 0.78 | GNAI3 (0.53) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL4902299 | 0.78 | GNAI3 (0.53) | GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL29086855 | 0.78 | GNAI3 (0.53) | GNAI3GNAO1GNAI1S1PR1S1PR3 | |
| SCHEMBL19710765 | 0.78 | GNAI3 (0.53) | GNAI3GNAO1GNAI1PAOX | |
| SCHEMBL27553097 | 0.78 | GNAI3 (0.53) | GNAI3GNAO1GNAI1PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125790-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-06-16 | — | — | WO | disclosed |