Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24173124 | 0.84 | GNAI3 (0.49) | GPR183GNAI3GNAO1GNAI1CHRM3 | |
| SCHEMBL28201825 | 0.80 | GPR183 (0.54) | GPR183GNAI3GNAO1GNAI1CHRM3 | |
| SCHEMBL4914342 | 0.79 | GNAI3 (0.50) | GNAI3GNAO1GNAI1 | |
| SCHEMBL24508482 | 0.79 | GNAI3 (0.46) | GPR183GNAI3GNAO1GNAI1CHRM3 | |
| SCHEMBL4902299 | 0.78 | GNAI3 (0.53) | GNAI3GNAO1GNAI1 | |
| SCHEMBL29086855 | 0.78 | GNAI3 (0.53) | GNAI3GNAO1GNAI1CHRM3KCNH2 | |
| SCHEMBL11871252 | 0.78 | GNAI3 (0.53) | GPR183GNAI3GNAO1GNAI1CHRM3 | |
| SCHEMBL19710765 | 0.78 | GNAI3 (0.53) | GNAI3GNAO1GNAI1 | |
| SCHEMBL22521105 | 0.78 | HRH2 (0.56) | GNAI3GNAO1GNAI1CHRM3DRD3 | |
| SCHEMBL11063714 | 0.78 | GNAI3 (0.48) | GPR183GNAI3GNAO1GNAI1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922431-A | HPK1 inhibitors and methods of use thereof | 大学健康网络 | 2018-04-17 | — | — | CN | disclosed |